Supply proton transfer reaction time-of-flight mass spectrometer

Proton transfer reaction time-of-flight mass spectrometer

Introduction to the device:
Kore's "Series II" high-performance PTR-TOF-MS can monitor the atmosphere and also apply true eddy covariance technology to extend ecosystem flux testing of volatile organic compounds (VOCs) composition and induction. The key requirement for these monitoring is to be able to simultaneously measure all relevant volatile compounds (proton affinity higher than H2O) and have sufficient sensitivity to all relevant volatile compounds. PTR-TOF-MS must be suitable for on-site or field testing, such as configuring a heated sampling pipeline with a 10 Hz time resolution, in order to use vorticity correlation technology for measuring plants.
The PTR-TOF-MS from Kore company has the following characteristics:
·High sensitivity to analytes and low detection limit
·High quality resolution for accurate identification of chemical components
·Durable, easy to transport, and convenient for on-site or field work.
Kore's PTR-TOF-MS adopts a new PTR reactor and is equipped with an ion concentrator designed as part of the reactor. It can greatly reduce the ion loss caused by the phenomenon of "space charge" and the mutual repulsion of high-density ions in the reactor. This new device can guide ions to the reactor outlet, generating a strong ion beam that enters the next area of the instrument. Kore's PTR-TOF-MS enables ion transport without the need for large aperturesMore efficientMaximize to obtain the required high-sensitivity ion current. The smaller the aperture, the smaller the required pumping capacity of the instrument, thus saving costs.
In addition, Kore's PTR-TOF-MS is equipped with a new mass spectrometer with high mass resolution. In ion transportMore efficientAt large, the basic resolution is ≥ 4000. If ion optics fine-tuning is used, the resolution can be increased to 5000 or higher, but there may be some loss in ion transport. The resolution of the mass spectrometer can be higher (up to 10000).
Proton transfer reaction time-of-flight mass spectrometer
The brief introduction of instrument specifications is as follows:
Kore "rack mounted" specifications
Quality resolution:>4000 m/Δ m (FWHM)
Quality range: 1-2000 m/z
Response time:<100 ms=''>
Sensitivity:>150 cps/ppbv (benzene, using N2 as equilibrium gas)
Detection limit (1 minute):<10 pptv=''>
Linear range: 5pptv-50ppmv
Pulse frequency: up to 80 kHz
Typical frequency: 20 kHz
Adjustable flow rate: up to 1000 sccm (standard cubic centimeter)
Primary ion beam: H3O+
Other primary ion beams: can replace other injection gases as ion sources to generate different reagent ions
Injection heating range: 50-200 ℃
Heating range of reaction chamber: up to 130 ℃
High speed TDC 4GHz
Vortex type oil-free vacuum pump
Power supply: 100-240 V
Dimensions (W x H x D): 61 x 168 x 80 cm
Weight: Approximately 225 Kg

PTR-TOF-MSmain components
1. Heating injection pipeline system
2. Hollow cathode glow discharge ion source, equipped with ion source drift
3. PTR reactor, equipped with ion concentrator, heating box and controller
4. Flight time ion source and mass spectrometer
5. Vacuum pump, controller, and measuring instrument (with fault protection components)
6. High speed TDC (4GHz time to digital converter)
7. Computer system+GRAMS AI+Kore software
8. Instrument rack and panel
9. System integration and testing
10. Operation Manual
11. Spare parts

Detailed introduction
1.Heating injection pipeline system
The heating injection pipeline we provide is suitable for on-site or field measurements. It also provides power supply for the heater, which can be controlled through instruments. Introduce the gas to be analyzed into the analysis injection port by heating the injection pipeline. If the gas pressure is much higher than atmospheric pressure or the gas flow rate is high, some of the gas to be analyzed is led out from the outlet of the instrument. There is a T-shaped tube between the inlet and outlet, and the gas to be analyzed is introduced through a capillary pipeline. The gas injection device is installed in a heating box, and the capillary line has an independent heater to introduce hot gas from the injection port into the PTR heating box. Users can select the temperature of the injection heating box and capillary heater through a simple user interface,Z高The temperature can reach 200 ℃. The instrument has a heater control panel that provides necessary heating control for various injection line heaters and PTR reactor heating boxes.

2.Hollow cathode glow discharge ion source and ion source drift region
The glow discharge ion source provides H3O+primary ion beam as standard configuration. The instrument is equipped with a heated water bottle and a transmission pipeline for heated water vapor, which is introduced into the glow discharge ion source. The temperature of the water bottle can be changed to keep it above room temperature. Eliminate the influence of external temperature changes on water vapor pressure.
Other gases can also be used as ion sources to obtain other types of chemical ionization. In our standard configuration, we provide ion source switching gas pipelines. Other gas ion sources can also be provided to customers.

3.PTRReactor, equipped with ion concentrator, heating box and controller
Directly behind the ion source drift zone is the PTR reactor, where the analyte molecules undergo proton transfer reactions with H3O+. Due to the presence of pressure in this region, the average free path is very short, and there are many opportunities for the analyte molecules to collide with H3O+ions. A series of electrostatic plates apply voltage gradients to the ion flux to be analyzed. Combined with the airflow, the ions are transported to the outlet of the PTR reactor.
Kore Company has added a new type of ion concentrator to the reactor. This can increase the flux of ions leaving the reactor, thereby increasing sensitivity and reducing detection limits.
The PTR reactor has a heating box equipped with three independent heaters to maintain the temperature of the reactor, which can reach 130 ℃. When it needs to be opened, the heating box is easily separated by quick release capture.
The electronic chassis can control the reactor and its related components: glow discharge ion source (cathode and anode), ion concentrator, reactor outlet ion energy, and extraction into the transfer lens. Read back the control pressure values of various parameters displayed on the panel instrument. During data collection, automatically measure PTR temperature and generate data file header information.

4.Flight time ion source and mass spectrometer
The next area after the PTR reactor is the lens transfer zone. It creates a buffer vacuum (medium vacuum) before entering the high vacuum of the mass spectrometer, and focuses ions (rather than neutral substances) through differential pumping holes, entering TOF. Then the TOF ion source creates ion pulses. These ions are introduced into the TOF mass spectrometer through a set of optimized deflectors for large pulse transmission without ion loss or distortion.
The TOF mass spectrometer used in the instrument is based on Kore's R-500-8 TOF-MS, which has a high mass resolution (up to 10000).
The ions from the TOF ion source fly in the "field free zone" before reaching the TOF-MS reflector, which is made of precision machined ceramic spacers and equipped with compatible ultra-high vacuum (UHV) and laser fine tuned resistors between different electrodes. These ions are reflected and returned through the field free region, hitting the detector.
The ion detector consists of a dual microchannel plate detector and is equipped with a preamplifier installed through a flange. In principle, our TOF-MS does not require the use of a "post acceleration" method and has no limitations on the detection mass range, except for extremely large mass ions (several thousand m/z) that cannot be effectively converted on the detector. The mass of gaseous molecules rarely exceeds 1000. The claim that the mass range of detectable gaseous compounds in the instrument is several thousand is misleading.
All of these are composed of ultra-high vacuum (UHV), and the stainless steel chamber is sealed with ultra-high vacuum conflat copper gaskets.
Kore's TOF-MS voltage controller provides all the necessary voltages for TOF ion sources and mass spectrometers.

5．Vacuum pump, controller, and measuring instrument (with additional fail safe protection components)
The extraction pump required for the PTR reactor needs to be able to update the gas inside the PTR reactor, so as to facilitate rapid and real-time analysis multiple times within 1 second. The "dry" vortex vacuum pump attached to the instrument can achieve this cleaning purpose. A 240 l/s turbo pump can extract the lens transfer chamber. The mass spectrometer and TOF ion source require the use of a 75 l/s turbo pump. Both pumps are equipped with air cooling fans.
Kore's pump controller can control two types of turbo pumps and display the output vacuum degree of the vacuum gauge. Use a baratron pressure gauge to monitor the pressure of the PTR ion source or glow discharge pressure, and use an inverted magnetron gauge to monitor the low vacuum in the spectrometer and detection chamber. During data collection, automatically measure PTR pressure and generate data file header information.

6.high-speedTDC（4GHztime-Digital Converter
The instrument is equipped with an ion counting system (compared to an analog detection system). The digital signal output from the preamplifier (one pulse per ion) is input to Kore's 4GHz time to digital converter (TDC). TDC is a compact timing device that can quickly record the time of a series of events relative to the signal initiation event (at time=0). The timing resolution is 0.25 ns, with minimal dead time and high data recording rate, and the experiment is repeated with reproducibility of *.

7. computer system+ GRAMS AI + KoreThe company's software
Computer systems, laptops'Z lowConfiguration: A display of at least 17 inches, iCore 7, backlit keyboard, 2Tb hard drive, 8Gb DDR RAM, 100 Mbs wired or wireless network, Z-low 160Gb ATA series drive, Blu ray burner. Windows 7 or higher operating system.
The recommended software package components are as follows:
GRAMS AI Spectroscopy Suite, Kore's graphical user interface and mass spectrometry extension software, used for displaying/manipulating TOF mass spectra. This kit is quite mature and has been successfully used for setting up, collecting, and displaying TOFMS mass spectra in various TOFMS systems of Kore company. The result of mass spectrometry is a single curve of accumulated intensity over time or mass.

Two different monitoring modes
1. The * mode is the "chromatography" mode, which collects data in cycles of several minutes. All recorded ion data is "streamed to the hard drive" in the form of a single file over time, and the data can be retrieved in a retrospective manner, allowing for viewing of time intervals of less than 50ms in the chromatographic direction.
There is no need to accurately analyze which components are of interest beforehand, as the "raw data" can be "reproduced" and can generate chromatograms of any ion. Similarly, data can also be reproduced, and mass spectra can be reconstructed for any "time slice" in the dataset.
This chromatography like 'function' is provided by the created data file, which records the arrival time of all detected ions. The software can convert these time lists into multiple mass spectrometry files, suitable for viewing with the GRAMS GC-MS browser. Using the GRAMS GC-MS browser, mass spectra of any "time slice" from past experiments can be created. In addition, the relationship between any change in mass number and time can generate a "chromatogram".
2. Another mode allows users to obtain a series of discrete mass spectra using user programmable delays during different data collection periods. This is more practical for long-term data collection, such as conducting 10 second data collection every 10 minutes for several hours.

Real time display of experimental progress, with the integration of user spectral peaks, displayed as a graphical curve on the computer screen.