Production type vacuum freeze dryer supplier

Effective area of the board layer:

2 m2

￠ 16 penicillin bottle quantity:

≥ 9000 pieces

￠ 22 penicillin bottle quantity:

≥ 4600 pieces

￠ 30 penicillin bottle quantity:

≥ 2600 pieces

Liquid product capacity:

≥ 40kg

□Production type freeze dryer(Freeze dryer) BIOCOOL brand specifications

Board size:

600 mm × 900 mm

Number of layers:

4+1 (radiation layer)

Interlayer spacing:

100 mm

The lowest temperature of the board layer:

≤ -55 ℃ (unloaded)

Cold trap with the lowest temperature:

≤ -70 ℃ (unloaded)

System ultimate vacuum degree:

≤ 5Pa

□ Infrastructure

Installed power:

15 KW

This is the installed power, not the operating power. Power consumption ＜<15 KWh

Water cooling heat dissipation area:

About 4 m2

□ Unit appearance and other parts

Dimensions (mm):

Approximately 1200 in width, 2500 in depth, and 2200 in height

Whole machine weight (Kg):

(Approximately) 1500

Noise:

≤ 70dB

Design, manufacturing, and installation standards:

According to relevant national regulations and standards such as the "Good Manufacturing Practice for Drugs", "Guidelines for the Implementation of Good Manufacturing Practice (GMP) for Drugs", and GB/T522 6.1-1996 standard

Complete Unit Verification:

The detection and verification plan, method, and corresponding instrument support.

Box material:

AISI 304 stainless steel

Box shape:

Horizontal rectangle

Internal surface roughness:

Ra≤0.5 μm

Opening direction of the box door:

Clockwise opening (viewed from above)

Freeze drying box door:

70mm thick organic glass door

Box door mirror:

Tempered glass (with light)

Box mirror:

Tempered glass (with light)

CIP rotating nozzle:

Top 2 pieces

Fixed nozzle for board layer:

One group per layer

◆

Vacuum control valve:

Ximat vacuum solenoid valve+Ximat needle type fine adjustment valve

□ Board layer components

Board material:

AISI 304 stainless steel

◆

Plate structure form:

Internal welding method with no solder joints on both the upper and lower surfaces

Surface roughness:

Ra ≤ 0.5 μm

Flatness of the board layer:

≤± 0.5 mm / m2

Interlayer spacing:

100 mm

Effective layer size:

600 mm × 900 mm

Number of layers:

6＋1

Effective area of the board layer:

2.16 m2

◆

The lowest temperature of the board layer:

≤ -55 ℃ (unloaded)

Cooling rate of the board layer:

≤ 40 minutes (from+20 ℃ to -50 ℃)

Heating rate of the board layer:

≤ 70 minutes (from -50 ℃ to+20 ℃)

Temperature difference between layers:

≤ ±0.5℃

Temperature range of the board layer:

-50℃ ～ +70℃

Pressure plug function:

Yes (top mounted, hydraulic)

Hydraulic cylinder:

Cylinder rod SUS304

Hydraulic pump station:

Motor Siemens

Protection:

The plate layer is directly welded and fixed with metal hoses and fluid dividers to ensure that the plate layer does not leak oil and is easy to clean during long-term movement. Protective strips are installed on the left, right, and rear sides of the plate layer to prevent the plates/bottles from exceeding the plate surface.

□ Cold trap

Cylinder material:

AISI 304 stainless steel

Cold trap form:

Vertical square trap

Cold trap sight glass:

Tempered glass (with light)

Coil material:

AISI 304 seamless stainless steel pipe

Surface roughness:

Ra ≤ 0.5 μm

Cold trap surface area:

≥ 4 m2

Freezing capacity:

≥ 40Kg

Cooling rate of cold trap:

+Reduce from 20 ℃ to -70 ℃ within 30 minutes

◆

Cold trap with the lowest temperature:

≤ -70 ℃ (no-load limit temperature)

Defrosting method:

Spray defrosting

□ Freezing system

freezer:

German BITZER (single machine dual level)

◆

Refrigerator model:

S4N-8.2Y

◆

refrigerant

R404A

Number of refrigerators:

1 unit

Board cooling:

1 unit (indirect refrigeration)

Plate layer constant temperature cooling:

1 unit (indirect refrigeration)

Cold trap refrigeration:

1 unit (direct cooling)

condenser

Water-cooled type

Freezing system protection and regulation device:

The products used are precise, stable, safe, and reliable.

Refrigeration components:

expansion valve

DANFOSS (Denmark)

Top cover valve

Cas (Italy)

solenoid valve

DANFOSS (Denmark)

oil separator

ALCO (USA)

High/Low Voltage Controller

DANFOSS (Denmark)

Oil pressure controller

DANFOSS (Denmark)

sight glass

DANFOSS (Denmark)

Angle type globe valve

CAS (France)

globe valve

DANFOSS (Denmark)

gas-liquid separator

ALCO (USA)

Exhaust temperature protection

DANFOSS (Denmark)

Liquid addition shut-off valve

DANFOSS (Denmark)

Intercooled plate heat exchanger

DANFOSS (Denmark)

Compressor heater

BITZER (Germany)

Compressor motor over temperature protection

BITZER (Germany)

Acid removal filter core

ALCO (USA)

pressure gauge

LR/REFCO (Germany/Switzerland) oil immersed pressure gauge

Refrigeration oil

BITZER (Germany)

Water-cooled condenser

special arts and crafts

□ Fluid circulation system

◆

Fluid:

Low viscosity silicone oil (25 ℃, 10 cSt)

Fluid pipeline material:

AISI 304 stainless steel seamless steel pipe, welded, with insulation

◆

Circulating pump:

GRUNDFOS wet rotor shielded pump from Denmark

★ The GRUNDFOS circulating pump from Denmark is

Number of circulating pumps:

a

Heating power:

4 KW

Heating method:

solid state relay

Stainless steel plate heat exchanger:

ALFA-LAVAL, Sweden

Temperature probe:

PT-100 Platinum Resistance/Thermocouple

□ Vacuum system

◆

Double stage rotary vane pump:

ULVAC VDN401 Double stage Rotary Disc Pump from Japan

quantity

1 unit

System's highest vacuum:

≤ 2Pa

Evacuation rate of freeze-drying box:

Atmospheric pressure → 10 Pa ＜ 40 minutes (under dry conditions)

System leakage rate:

≤ 10 Pa·l / sec

◆

Vacuum probe:

Zhenghua

◆

Main isolation valve:

Ximat DN200 Butterfly Valve (Pneumatic)

Trap isolation valve:

Ximat DN65 butterfly valve (pneumatic)

Backfilling solenoid valve for the box:

Ximat pneumatic vacuum baffle valve

Vacuum regulating valve:

Ximat High Vacuum Fine Adjustment Valve

Vacuum control valve:

Ximat vacuum shut-off valve

filter:

0.22μm, Polytetrafluoroethylene

Vacuum pump oil:

ULVAC

□ CIP system

Boosting pump:

GRUNDFOS (Denmark)

Water ring pump:

SHIHI (Germany)

Box inlet valve 1:

Dengyi (Pneumatic)

Box inlet valve 2:

Dengyi (Pneumatic)

Box outlet valve:

Dengyi (Pneumatic)

Trap inlet valve:

Dengyi (Pneumatic)

Trap outlet valve:

Dengyi (Pneumatic)

Trap overflow valve:

Dengyi (Pneumatic)

Water ring pump shut-off valve:

Dengyi (Pneumatic)

Pneumatic system

Two copies:

Taiwan, China Yaguan

Busbar:

Taiwan, China Yaguan

Box trap electromagnetic directional valve:

Taiwan, China Yaguan

Trap electromagnetic directional valve:

Taiwan, China Yaguan

Backfilling electromagnetic directional valve:

Taiwan, China Yaguan

Defrosting electromagnetic directional valve:

Taiwan, China Yaguan

Box inlet electromagnetic directional valve 1:

Taiwan, China Yaguan

Box inlet electromagnetic directional valve 2:

Taiwan, China Yaguan

Box outlet electromagnetic directional valve:

Taiwan, China Yaguan

Trapped water inlet electromagnetic directional valve:

Taiwan, China Yaguan

Trapped water magnetic directional valve:

Taiwan, China Yaguan

Trap overflow electromagnetic directional valve:

Taiwan, China Yaguan

Water ring pump shut-off valve:

Taiwan, China Yaguan

□ Plate laminated plug system

Operation method:

hydraulic

Hydraulic cylinder position:

Bottom of freeze-drying box

Double one-way throttle valve:

YUKEN

Dual liquid control one-way valve:

YUKEN

Electromagnetic directional valve:

YUKEN

Liquid flow valve:

YUKEN

motor

Siemens

Pressure relay:

Schneider

◆

Hydraulic station:

special examination

• The main hydraulic components are produced by Italian company ATOS and American company SUN

□ Control system

◆

Control method:

Automatic control system (touch screen+PLC)

The automatic control system adopts closed-loop control mode

• The automatic control system adopts a touch screen as the upper computer and a PLC (programmable logic controller) as the lower computer for automatic control.

◆

touch screen:

Japanese Proface

◆

PLC (Programmable Logic Controller):

Siemens, Germany

communication cable

Siemens, Germany

Intermediate relay:

OMRON Japan

AC contactor:

Siemens, Germany

Air circuit breaker:

Siemens, Germany

Thermal relay:

Siemens, Germany

Solid state relay:

Siemens, Germany

Fuse:

Siemens, Germany

Switching power supply:

Siemens, Germany

thermostat:

Samsung

Alarm indicator light:

Taiwan, China

terminal

Phoenix

□ System functions

Control method

Manual, semi-automatic, and automatic control modes

temperature control

Controllable heating rate

lyophilization process

Freeze drying curve, actual curve, and theoretical curve can be set for fitting

recipe

Can store N sets of formulas for convenient production

User Management

User level and password can be set, and operation management can be decentralized

other

Monitoring (data, event operation statistics), alarm function

□ Signal monitoring

Freeze drying box

Vacuum pressure measurement

cold trap

Vacuum pressure measurement

Import and export of silicone oil

temperature measurement

lamina

Measurement of each layer of sample

cold trap

temperature measurement

refrigeration system

High pressure monitoring

refrigeration system

Medium pressure monitoring

refrigeration system

Low pressure monitoring

refrigeration system

Oil pressure monitoring

refrigeration system

Water pressure monitoring

Silicone oil system

Oil pressure monitoring

hydraulic system

Oil level monitoring

hydraulic system

Liquid level monitoring

hydraulic system

Ascending position monitoring

hydraulic system

High pressure monitoring

pneumatic system

Pressure monitoring

□ Security protection

Whole machine startup protection:

The whole machine can only start running when all safety conditions of the equipment are met.

Operation protection:

The electrical system of the whole machine has logical interlocking, control, and protection functions.

motor

There are overload, overheating, phase loss protection, etc

Freezing system:

There are sound and light alarms, and each component has a controller

Vacuum pressure:

There is an audible and visual alarm

heating system

There is an audible and visual alarm

Power outage and supply:

All have safety protection measures in place

Circulating system:

Heating cycle protection

Product protection during sublimation process:

• Cut off heating when the vacuum degree is poor

• When the vacuum degree is too good, it can be automatically adjusted.

Cold trap protection for vacuum pump startup:

chain

Refrigeration:

High and low voltage protection

water cooling

water pressure protection

compressor:

Oil pressure and temperature protection

□ Complete equipment

power supply

Three phase 380V

Installed power:

15KW ★ This is the installed power, not the operating power.

Whole machine structure:

The whole machine is integrated (vertically mounted)

Temperature measurement:

Each layer is assembled

CIP：

Online cleaning of box traps and pipelines

SIP：

Optional box trap and pipeline online disinfection

Deionized water usage:

80L/M

Cooling water:

110L/M

compressed air

0.4-0.6Mpa

Whole machine decorative panel

SUS304

spray painting

imported eco-friendly paint

Chassis and substrate

8mm steel plate

thermal insulation material

Imported Alfaro

packaging material

Non fumigation environmentally friendly materials

五金材料

domestic

wire and cable

domestic

Wire trunking and electrical insulation lining board

domestic

Dimensions (mm):

Approximately 1200 in width, 3000 in depth, and 3300 in height

Total weight of the machine

(Approximately) 1500 kg

Price:

798 thousand and 800