Ethylene oxide residual gas chromatograph company

Disposable Class III medical devices are one of the medical devices with large clinical usage and wide area. These products must be sterilized before leaving the factory, mainly using high-pressure fumigation with ethylene oxide for sterilization treatment. Ethylene oxide（EO）Has broad-spectrum and efficient effects, can kill various microorganisms (including spores, viruses, fungi, etc.) at room temperature),But it belongs to toxic gases, which are easily adsorbed on various substances and have a significant toxic effect on the human body. In addition to general acute toxicity, ethylene oxide can also cause teratogenic mutations in many cases. The manufacturer is responsible forEODisinfected products need to undergo a period of analysis to release any residues. In order to protect the safety of the product in clinical use, it is necessary to determine the residual amount of ethylene oxide in sterilization products.

This method uses headspace gas chromatography to determine the residual amount of ethylene oxide, and the results are accurate and reliable.

1.Instruments and reagents

1.1Instrument gas chromatograph precision measurementGC-9800GFIDDetector; Headspace sampler; electronic balance

1.2Reagent ethylene oxide reference standard, re distilled water, sample containing ethylene oxide

2.method

2.1Gas chromatography conditions capillary chromatography column30m*0.45mm*2.55um；N2 3ml/min；H2 45ml/min；AIR 450ml/minColumn Room90Degree; Gasification room220Degree; Testing Room250Degree; split ratio5：1

Main technical indicators:
1Temperature control indicators：
pillar Box: at room temperature8℃－420℃precision±0.1℃(200℃Time measurement).
Sample injector: at room temperature8℃－420℃precision±0.1℃(200℃Time measurement).
Detector: at room temperature8℃－420℃precision±0.1℃(200℃Time measurement).
Up to six temperature control channels: suitable for multiple temperature control requirements such as installing conversion furnaces.
2Column temperature box parameters:
Temperature control accuracy: at room temperature8℃－399℃precision±0.1℃.
Column temperature box volume:280mm×280mm×250mm.
Program heating order: eight orders.
Program heating rate:1℃－50℃.
Constant temperature holding time for each stage:0－300min（1minIncremental).
Automatic rear door design ensures rapid cooling.
A high-power, low-noise rotating fan ensures temperature uniformity.
3Stable dual air system:
The carrier gas flow rate adopts a dual stability design of first stabilizing and then stabilizing the flow.
Accurate scale type pneumatic control valve components with high reproducibility and stability.
4Multiple injection methods are available:
Fill the column head for injection.
Filling column gasification injection.
Capillary diversion/Non diversion injection: Back pressure valve control technology, linear diversion.
Six way valve gas injection.
Online sampling: unattended situation24Continuous injection for hours.

5、Five detectors to choose from

Hydrogen flame ion detector(FID)Used for organic matter analysis in the hydrocarbon industry and other fields.
thermal conductivity detector(TCD)： Used for constant analysis of gases and liquids.

Nitrogen and phosphorus detector(NPD)： Used for the detection of trace sulfur and phosphorus compounds.
Flame photometric detector(FPD)Used for the detection of trace sulfur and phosphorus compounds.
Electron capture detector(ECD)Detect compounds that can capture electrons.

3、 High sensitivity detector parameters ensure the accuracy of data